The EClassical 3200L UHPLC system was coupled with the MS2 Vertical 9020 triple quadrupole mass spectrometer in the Elite MS2 Vertical 9020 LC-MS/MS system. This configuration fully leverages the advantages of the EClassical 3200L HPLC system, including its intelligent design, ultra-high performance, "rapid injection," and long-term stable and precise operation. Simultaneously, it integrates high sensitivity, high stability and high cost-effectiveness, with the advantages of strong quantitative ability and multiple reaction modes of Elite MS2 Vertical 9020. This combination achieves rapid, sensitive, convenient, and stable long-term LC-MS/MS testing and operation. The system can be widely used in the fields of medical research, biopharmaceuticals, food safety and environmental testing.
Liquid Chromatography Section (EClassical 3200L) ensures excellent separation and injection performance: the column oven provides temperature control with an accuracy of 0.1°C and supports multiple temperature control modes; the autosampler features an "Extreme Speed Injection" mode with injection times as fast as 1 second and includes cooling to ensure sample stability; the system offers a wide flow range (0.0001 – 5.0000 mL/min) and withstands pressures up to 130 MPa, meeting diverse method development needs.
The MS2Vertical 9020 triple quadrupole mass spectrometer delivers reliable and versatile performance for demanding analyses. It features a curved collision cell that effectively eliminates memory effect and cross-contamination, ensuring data integrity during high-throughput runs. The system is equipped with a high-precision, thermally stable quadrupole mass analyzer covering a broad mass range (m/z 5-3000), enabling the detection of high-mass organic compounds. Additionally, its ESI/APCI ion source supports temperatures up to 750°C, providing flexibility to meet diverse analytical requirements.
Ion source: heated auxiliary gas design, enabling temperature ramp-up to 650°C+ within 30 seconds; flow rate range 1 μL/min ‒ 3 mL/min, with no splitting required; plug-and-play design, allowing replacement without additional tools or venting; integrated exhaust trap assembly, preventing gas backflow in the sealed ion source enclosure.
Ion transport: cone design effectively prevents sample decomposition caused by thermal fragmentation and clogging caused by condensation; pre-quadrupole as an ion focusing guide device provides high contamination resistance; the ion source interface employs backflush technique and a removable skimmer cone.
Quality analyzer: cylindrical quadrupoles manufactured from high-purity molybdenum with gold-plated surfaces, ensuring exceptional mass axis stability; pre-ion guide design effectively eliminates fringe field effects, enabling superior ion focusing and anti-contamination functions; curved collision cell design efficiently eliminates memory effects and cross-contamination.
Vacuum system: turbomolecular pump with reliable vacuum-seal interface, enabling high-stability multi-stage gradient vacuum; ion source removable under vacuum, ensuring long-term robustness and experimental efficiency; automatic power-off protection, with no additional water cooling required.