SinoPak C18

SinoPak Series SinoPak chromatographic packing utilizes a novel ultra-pure silica matrix characterized by narrow particle size distribution and low metal impurity content. Its most popular C18 bonded phase is distinguished by an exceptionally high surface bonding density, making it an ideal choice for the separation of various organic compounds. Suitable for isolating most neutral, acidic, and alkaline compounds as well as chelated samples, SinoPak C18 can also be bonded with multiple functional groups including C8 and Phenyl phases, offering versatile solutions to meet diverse separation requirements.

Perfectly spherical silica gel with narrow particle size distribution
Excellent chromatographic peak shape
Superior selectivity and separation capability
Outstanding batch-to-batch reproducibility
Exceptional mechanical strength and extended column lifetime
Excellent resistance to acidic and alkaline conditions

SinoPak C18

The new silicone ultra-pure matrix, bonded with octadecylsilane, has better mechanical strength, narrow particle size distribution, excellent batch reproducibility and long lifespan.
It has a larger surface bonding coverage and carbon loading, making it an ideal choice for the separation of organic compounds. It is suitable for analyzing complex samples of traditional Chinese medicine.
It has excellent selectivity and separation ability, and can achieve excellent peak shapes.
The pH tolerance range is wide, and it is widely applicable.

SinoPak Packing Parameters

Stationary Phase	Particle Size (μm)	Specific Surface Area (m²/g)	Pore Size (Å)	Carbon Content (C%)	End-capping
SinoPak C18	3/5	300	120	21	Y

Application

1.Thiabendazole 2.O-phenylphenol 3.Diphenyl

Thiabendazole,O-phenylphenol and Diphenyl Analysis

Column: SinoPak C18, 5 μm, 4.6 mm × 250 mm
Mobile phase: Precisely weigh 0.681g of sodium dodecyl sulfonate, add 350 mL of methanol, 50 mL of acetonitrile, 100 mL of water and 1 mL of phosphoric acid, mix well, filter and then use.
Flow rate: 0.5mL/min
Detection: 247 nm
Injection volume: 20 μL
Column temperature: 40 °C

Aspartame, benzoic acid, sorbic acid, saccharin sodium Analysis

Column: SinoPak C18, 5 μm, 4.6 mm × 250 mm
Mobile phase: Methanol: 0.02 mol/L ammonium acetate = 10 : 90
Flow rate: 1.0 mL/min
Detection: 230 nm
Injection volume: 10 μL
Column temperature: 30°C

How It Works

The new silicone ultra-pure matrix, bonded with octadecylsilane, has better mechanical strength, narrow particle size distribution, excellent batch reproducibility and long lifespan. It has a larger surface bonding coverage and carbon loading, making it an ideal choice for the separation of organic compounds. It is suitable for analyzing complex samples of traditional Chinese medicine.

Hydrogen Bonding Capacity Test Chromatogram

Effective End-capping

Chromatographic column: SinoPak C18 5μm, 4.6×150 mm
Mobile phase: Methanol / Water = 30 / 70
Flow rate: 1.0 mL/min
Wavelength: 254 nm
Column temperature: 30°C
Test compounds: 1. Uracil, 2. Caffeine, 3. Phenol

Test Item	Evaluation Metric	Detection Result	Conclusion	Reference Criteria
Hydrogen bonding capacity	α caffeine/phenol	0.37	Low binding capacity	≤0.6,Low binding capacity＞0.6,High binding capacity

Chromatographic column: SinoPak C18 5μm, 4.6×150 mm
Mobile phase: Methanol : 20 mmol/L phosphate buffer (pH 2.7) = 30 : 70
Flow rate: 1.0 mL/min
Wavelength: 254 nm
Column temperature: 30°C
Test compounds: 1. Uracil, 2. Aniline, 3. Phenol

Test Item	Evaluation Metric	Detection Result	Conclusion	Reference Criteria
Ion exchange sites	α aniline/phenol	0.06	Relatively few exchange sites	≤0.2,Relatively few exchange sites0.2-0.4,Moderate exchange sites＞0.4, Many exchange sites

Excellent Hydrophobic Selectivity and Stereoselectivity

Chromatographic column: SinoPak C18 5μm, 4.6×150 mm
Mobile phase: Methanol : Water = 80 : 20
Flow rate: 1.0 mL/min
Wavelength: 254 nm
Column temperature: 30°C
Test compounds: 1. Uracil, 2. Butylbenzene, 3. Terphenyl, 4. Pentylbenzene, 5. Triphenylene

Test Item	Evaluation Metric	Detection Result	Conclusion	Reference Criteria
Hydrophobic Selectivity	α Pentylbenzene/Butylbenzene	1.49	High Selectivity	≤1.3,Low Selectivity1.3-1.45,Medium Selectivity＞1.45,High Selectivity
Stereoselectivity	α Triphenylene/o-Terphenyl	1.69	High Selectivity	≤1.3,Low Selectivity1.3-1.45,Medium Selectivity＞1.45,High Selectivity

Excellent Batch Repeatability

Ordering Information

Stationary Phase	Particle Size (μm)	Size (mm)	P/N
SinoPak C18	3	4.6×50	31111208-C
	3	4.6×100	31111209-C
	3	4.6×150	31111210-C
	5	4.6×150	31110107-C
	5	4.6×200	31110108-C
	5	4.6×250	31110109-C

*For column specifications not mentioned, please contact us for further information.

SinoPak C18

Application

Thiabendazole,O-phenylphenol and Diphenyl Analysis

Aspartame, benzoic acid, sorbic acid, saccharin sodium Analysis

How It Works

Effective End-capping

Excellent Hydrophobic Selectivity and Stereoselectivity

Ordering Information

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